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cheap itraconazole The change, which will take effect over the next three years, is the first serious attempt by the federal government to curb the broad use of antibiotics in farm animals in decades. Pressure for action has mounted as the effectiveness of drugs important for human health has declined, and deaths from bugs resistant to antibiotics have soared. Food producers said they will abide by the rules, but some public health advocates voiced concerns that loopholes could render the policy toothless.